Fig. 4
Effect of enriching the precursor L-Trp pool on 5-HTP production. a Cell growth, 5-HTP production and L-Trp accumulation of HTP06-09 strains after 26-h period of cultivation in shake flasks with glucose as carbon source. b Yield of HTP07-09 strains. The genotype of strains: HTP07, HTP06 trpLE::Ptrc-trpEfbr; HTP08, HTP07 yjiV::Ptrc-aroGfbr; HTP09, HTP08 ycgH::Ptrc-serAfbr. The data are presented as averages, and the error bars represent standard deviations (n = 3 independent experiments). * 0.01 < P < 0.05, ** P < 0.01. ND, not detected