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Fig. 2 | Microbial Cell Factories

Fig. 2

From: An accurate strategy for pointing the key biocatalytic sites of bre2691A protein for modification of the brevilaterin from Brevibacillus laterosporus

Fig. 2

Phylogenetic analysis of A domain. a The sequences of the following 15 A domains were used for phylogenetic analysis and their specificity-conferring codes. B. laterosporus Bre2691A (this study), B.subtilis SrfA-C [29], B. brevis PheA [14], B. parabrevis LgrA [30], Streptomyces lydicus SlgN1 [11], Geobacillus sp. Y4.1MC1 DhbF [31], Thermobifida fusca YX FscH, Streptomyces SP.OH-5093 THR1, Streptomyces sp. CytC1, B. cereus ATCC 14,579 DltA [35], Epichloe festucae var. lolii SidN [36], Streptomyces sp. ML694-90F3 IdnL1, Streptomyces sp. MJ635-86F5 CmiS6, Streptomyces halstedii VinN, B. subtilis DhbE [37]. b the specificity-conferring codes from 15 A domains according to the PheA numbering. c and d Conserved core motifs in fifteen A domains. b the location of A1, A2 and A3 positions showed at number 18, 19 and 22. c the location of A10 position showed at number 9

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