Fig. 4

Establishment of a possible regulatory network for the production of TNMs: A The EMSA results of 7 biotin-labeled promoter regions with or without the presence of TnmR1; B The proposed delicate regulatory network to control the biosynthesis of TNMs (the black solid line means the results of TnmR1 were validated by both qRT-PCR and EMSA, the red dash line means the results of TnmR7 were deduced from qRT-PCR, the black bold dash line indicates the enhanced regulations of phosphorylated TnmR1, the blue dash box means the result was speculated from the genetical characterization)