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Fig. 1 | Microbial Cell Factories

Fig. 1

From: Enhanced production of amyrin in Yarrowia lipolytica using a combinatorial protein and metabolic engineering approach

Fig. 1

Biosynthesis of α- and β-amyrins in the engineered Y. lipolytica. Extracellular carbon sources were assimilated and converted into α- and β amyrins via the mevalonate (MVA) pathway. Metabolites are identified in black. Endogenous and foreign genes that were up-regulated are listed in red and green, respectively. HMG1: hydroxymethylglutaryl-CoA reductase; ERG20: farnesyl diphosphate synthase; ERG9: squalene synthase; ERG1: squalene monooxygenase; CrMAS: C. roseus multifunctional amyrin synthase

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Microbial Cell Factories

ISSN: 1475-2859

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