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Fig. 9 | Microbial Cell Factories

Fig. 9

From: Oral or intranasal immunization with recombinant Lactobacillus plantarum displaying head domain of Swine Influenza A virus hemagglutinin protects mice from H1N1 virus

Fig. 9

Assessment of lymphoproliferative responses and comparison of cytokine profiles in splenocyte culture supernatants restimulated with recombinant H1N1 HA1 antigen. a, e Three mice in each group were sacrificed 7 days after the third immunization, and splenocytes proliferation in response to antigen stimulation was estimated using an MTT assay. Values are presented as the mean ± SD for three samples. Differences between all immunized and control groups were statistically highly significant (p < 0.001). b–d and f–h The ELISA results are representative of three independent experiments and are expressed as the mean ± SD. One-way ANOVA was used to analyze differences among groups. ***, P < 0.001; **, p < 0.01. The graphs also show a statistically significant difference between all vaccinated and control groups (P < 0.001)

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Microbial Cell Factories

ISSN: 1475-2859

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