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Table 3 ANOVA results for the quadratic models describing arabitol concentration and glycerol conversion yield as function of glycerol concentration (A), temperature (B), pH (C), and DOT (D) together with model performance parameters

From: Improved fed-batch processes with Wickerhamomyces anomalus WC 1501 for the production of d-arabitol from pure glycerol

Response

Source

Sum of Squares

Degrees of

freedom

Mean

Square

F value

p-value

Prob > F

Arabitol

Model

1272.84

6

212.14

31.51

< 0.0001

 

A

185.93

1

185.93

27.61

< 0.0001

 

B

416.67

1

416.67

61.88

< 0.0001

 

C

106.68

1

106.68

15.84

0.0006

 

AB

186.32

1

186.32

27.67

< 0.0001

 

A2

331.54

1

331.54

49.24

< 0.0001

 

B2

76.42

1

76.42

11.35

0.0027

 

Residual

154.86

23

6.73

  
 

Lack of fit

145.90

18

8.11

4.53

0.0512

 

Pure error

8.95

5

1.79

  
 

R-squared

    

0.89

 

Adj R-squared

    

0.86

 

Pred R-squared

    

0.78

 

Adeq precision

    

21.6

Conversion yield

Model

0.090

6

0.015

10.83

< 0.0001

 

A

6.534·10− 3

1

6.534·10− 3

4.72

0.0404

 

B

0.031

1

0.031

22.25

< 0.0001

 

C

0.024

1

0.024

17.10

0.0004

 

AB

6.806·10− 3

1

6.806·10− 3

4.91

0.0368

 

A2

0.017

1

0.017

12.23

0.0019

 

B2

7.425·10− 3

1

7.425·10− 3

5.36

0.0299

 

Residual

0.032

23

1.385·10− 3

  
 

Lack of fit

0.031

18

1.739·10− 3

15.62

0.0032

 

Pure error

5.568·10− 4

5

1.114·10− 4

  
 

R-squared

    

0.74

 

Adj R-squared

    

0.67

 

Pred R-squared

    

0.52

 

Adeq precision

    

11.1

  1. Only the terms with significant effect (P < 0.05) and those that have significant interactions were retained in the model and reported herein