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Fig. 4 | Microbial Cell Factories

Fig. 4

From: Enzymatic basis of the Fc-selective intra-chain disulfide reduction and free thiol content variability in an antibody produced in Escherichia coli

Fig. 4

Effect of homogenate hold (0, 4, and 12 h hold) on a Total free thiol content in mAb1 MSS pools, b Site specific free thiol content of mAb1 MSS pools. HH (homogenate hold), DS (manufacturing-scale produced drug substance with minimal homogenate hold step (< 1 h)). Results shown are for n = 1 sample

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