Fig. 1
Pressure build-up and flow rate during depth filtration of fermentation broth. Centrifuged culture broth was filtered with comercial depth filters to further reduce particle content. The blue scatter plots indicate the pressure during flitration. The red scatter plots indicate the LMH (Liter per m2 per hour) calculated based on filtrate weight and filter area. a Pressure and LMH of the run with the 60SP02A filter capsule plotted over weight of the filtrate. The pressure reached 2 bar after about 1.6 L and the flow rate dropped by a factor of 4. b Pressure and LMH of the run with the 30SP02A filter capsule plotted over weight of the filtrate. The pressure reached 2 bar after about 9 L while the flow rate dropped by a factor of 3