Metabolic engineering of Corynebacterium glutamicum for efficient production of optically pure (2R,3R)-2,3-butanediol

Table 2 Summary of literature on microbial fermentation for the optically pure (2R,3R)-2,3-butanediol production above 100 g/L

Strains	Substrates	Titer (g/L)	Purity (%)	Yield (g/g substrates)	Productivity (g/L/h)	Refs.
Corynebacterium glutamicum CGK4	Glucose	144.9	98	0.43	1.10	This study
Enterobacter cloacae SDM 09	Glucose and xylose	152.0	97.5	0.49	3.5	[23]
Enterobacter cloacae SDM 09	Corn stover hydrolysate	119.4	96	0.48	2.3	[23]
Saccharomyces cerevisiae JL0432	Glucose and galactose	100	98	0.35	0.33	[45]
Bacillus licheniformis MW3△budC	Glucose	123.7	99	NM	2.95	[14]
Escherichia coli MQ1	Glucose	115	99	0.42	1.44	[46]
Paenibacillus polymyxa DSM 365	Sucrose	111	98	0.48	2.06	[20]
Klebsiella oxytoca ΔldhAΔpflB ΔbudC::PBDH(pBBR-PBDH)	Glucose	106.7	92	0.40	3.1	[47]
Bacillus subtillis FJ-4	Glucose	100.0	99.9	0.44	0.6	[48]

ISSN: 1475-2859