Fig. 5
From: Engineering heterologous enzyme secretion in Yarrowia lipolytica
Overview of the strategies applied in the secretory pathway engineering [9, 24, 26]. Exported mRNA from nucleus was co-translated and translocated into ER. The ER membrane was engineered by deleting PAH1 gene and direct the phospholipid acid for the synthesis of ER. PA, phospholipid acid; DAG, diacylglycerol; TAG, triacylglycerol; LD, lipid droplet; ERV29, ER exit receptor