Skip to main content
Fig. 2 | Microbial Cell Factories

Fig. 2

From: Bottom-up synthetic biology approach for improving the efficiency of menaquinone-7 synthesis in Bacillus subtilis

Fig. 2

Increasing the precursor supply to push carbon into the MK-7 synthesis pathway. a Schematic for the overexpression of dxs, fni, dxr, menF, and aroA in the genome of the BS168 under the regulation of the promoters P43 or Phbs, resulting in the generation of recombinant strains BS001 through to BS005. b Growth curves for BS168, BS001, BS002, BS004, and BS005. c Production of MK-7 in BS168, BS001, BS002, BS004, and BS005 after 120 h fermentation. All experiments were performed in triplicate and error bars represent the standard deviation (SD)

Back to article page