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Fig.1 | Microbial Cell Factories

Fig.1

From: Commensal bacteria-derived extracellular vesicles suppress ulcerative colitis through regulating the macrophages polarization and remodeling the gut microbiota

Fig.1

C. butyricum-derived EVs suppressed the progression of acute DSS-induced colitis. a Nanoparticle tracking analysis (NTA) for characterization of C. butyricum-derived EVs. b Transmission electron microscopy images of isolated EVs. Scar bar was 100 nm. c Ex vivo image of gastrointestinal tract, after 8 h of EVs feeding. d Mice were given 5 days of 2% DSS treatment to induce acute colitis, followed by intragastrical administration of C. butyricum-derived EVs in the next 5 days, or treated with drinking water as control (n = 6 per group). e DAI, f body weight change, and g colon length was measured at the indicated time points. h H&E and AB-PAS staining of each treatment group. Scar bars were 100 μm, respectively. Data are presented as means ± SD, n = 6 mice per group. *P < 0.05; **P < 0.01; ***P < 0.001

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