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Fig. 1 | Microbial Cell Factories

Fig. 1

From: De novo biosynthesis of p-coumaric acid and caffeic acid from carboxymethyl-cellulose by microbial co-culture strategy

Fig. 1

Schematic illustration of the co-culture system of different metabolically engineered S. cerevisiae strains for de novo biosynthesis of p-CA and CA from CMC. In this system, CMC in medium was degraded by cellulolytic enzymes expressed in SK10-3 by the POT1-mediated δ-integration strategy. The released glucose was assimilated by SK10-3 and other co-culture strains to yield p-CA or CA. PEP: phosphoenolpyruvate; EPSP: 5-enolpyruvylshikimate-3-phosphate; Trp: tryptophan; Phe: phenylalanine; Tyr: tyrosine; p-CA: p-coumaric acid; CA: caffeic acid

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