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Fig. 1 | Microbial Cell Factories

Fig. 1

From: Improving astaxanthin production in Escherichia coli by co-utilizing CrtZ enzymes with different substrate preference

Fig. 1

Schematic diagram of the heterologous synthesis pathway for the production of carotenoids. MVA Pathway mevalonic acid pathway, MEP Pathway 2-methyl-D-erythritol-4-phosphate pathway, DMAPP dimethylallyl pyrophosphate, IPP isopentenyl pyrophosphate, GGPP geranylgeranyl pyrophosphate; Genes of enzymes are as follows: ispA, Farnesyl pyrophosphate synthase; crtE, GGPP synthase; crtB: phytoene synthase; crtI: phytoene desaturase; crtY: lycopene cyclase; PAcrtZ, β-carotene hydroxylase from P. agglomerans; PCcrtZ, Paracoccus sp. PC1; crtW*, mutated β-carotene ketolase; crtZ, β-carotene hydroxylase from P. agglomerans or Paracoccus sp. PC1

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