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Fig. 1 | Microbial Cell Factories

Fig. 1

From: Altering the fatty acid profile of Yarrowia lipolytica to mimic cocoa butter by genetic engineering of desaturases

Fig. 1

Overview of fatty acid synthesis in Yarrowia lipolytica and engineering strategy of the study. A The three main fatty acid species found in cocoa butter are marked with a cocoa pod. Names in blue display the proteins catalyzing the reaction. Fas fatty acid synthetase, Elo2 fatty acid elongase, Ole1 Δ9 fatty acid desaturase, Fad2 Δ12 fatty acid desaturase. B The three main experimental strategies of this study: first, the native OLE1 was exchanged with homologs to abolish palmitoleic acid (C16:1). Second, the native OLE1 promoter was exchanged to balance palmitic, stearic and oleic acid (C16:0, C18:0 and C18:1). Finally, the FAD2 promoter was exchanged to reduce the linoleic acid content (C18:2)

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Microbial Cell Factories

ISSN: 1475-2859

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