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Fig. 1 | Microbial Cell Factories

Fig. 1

From: Improved production of 2′-fucosyllactose in engineered Saccharomyces cerevisiae expressing a putative α-1, 2-fucosyltransferase from Bacillus cereus

Fig. 1

2′-FL biosynthesis and production optimization in S. cerevisiae. Lac12, Gmd, WcaG and α-1, 2-FT were heterologously overexpressed in S. cerevisiae for the biosynthesis of 2′-FL. Pmi40 and Sec53 were overexpressed to improve 2′-FL production by enhancing the GDP-mannose supply. Full names of enzymes in the figure: Lac12: Lactose permease; Gmd: GDP-mannose-4, 6-dehydrogenase; WcaG: GDP-4-keto-6-deoxymannose-3, 5-epimerase-4-reductase; FutBc: α-1, 2-fucosyltransferase; Pmi40: mannose-6-phosphate isomerase; Sec53: phosphomannomutase; Psa1: GDP-mannose pyrophosphorylase

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Microbial Cell Factories

ISSN: 1475-2859

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