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Table 1 Accumulation of aromatic compounds by ∆vdhA, ∆vhyA,mhdA and ∆omeA after 24 h of incubation

From: Vanillic acid and methoxyhydroquinone production from guaiacyl units and related aromatic compounds using Aspergillus niger cell factories

Starting substrate

Detected products

Reference

vdhA

vhyA

mhdA

omeA

Conc. (mmol/L)

Conc. (mmol/L)

Conc. (mmol/L)

Conc. (mmol/L)

Conc. (mmol/L)

Coniferyl alcohol

Vanillic acid

4.78 ± 0.07

Methoxyhydroquinone

3.67 ± 0.14

Unknown compounda

Detected

Ferulic acid

Vanillic acid

4.80 ± 0.09

Methoxyhydroquinone

3.93 ± 0.12

Unknown compounda

Detected

Vanillyl alcohol

Vanillyl alcohol

1.79 ± 0.37

1.24 ± 0.25

2.13 ± 0.15

2.75 ± 0.14

0.63 ± 0.32

Vanillin

0.08 ± 0.04

0.02 ± 0.04

Vanillic acid

2.80 ± 0.06

Methoxyhydroquinone

3.13 ± 0.13

Unknown compounda

Detected

Vanillin

Vanillin

4.02 ± 0.13

2.98 ± 0.75

0.29 ± 0.37

0.02 ± 0.04

Vanillyl alcohol

0.23 ± 0.05

0.64 ± 0.17

0.48 ± 0.09

0.49 ± 0.26

Vanillic acid

1.58 ± 0.71

0.07 ± 0.00

Methoxyhydroquinone

3.39 ± 1.28

Unknown compounda

Detected

Vanillic acid

Vanillic acid

4.82 ± 0.19

0.80 ± 0.89

Methoxyhydroquinone

4.04 ± 0.41

Unknown compounda

Detected

Veratryl alcohol

Veratryl alcohol

3.83 ± 0.34

3.73 ± 0.38

4.04 ± 0.18

3.76 ± 0.44

3.61 ± 0.67

Veratric acid

0.09 ± 0.02

0.65 ± 0.18

0.16 ± 0.07

0.08 ± 0.03

Vanillic acid

1.11 ± 0.05

Methoxyhydroquinone

2.11 ± 0.32

Unknown compounda

Detected

Veratric aldehyde

Veratric aldehyde

0.62 ± 0.02

2.00 ± 0.19

0.76 ± 0.00

0.75 ± 0.05

0.70 ± 0.05

Veratric acid

0.17 ± 0.13

0.40 ± 0.04

0.39 ± 0.13

0.18 ± 0.10

Vanillic acid

3.48 ± 0.04

Methoxyhydroquinone

3.27 ± 0.30

 

Unknown compounda

Detected

Veratric acid

Veratric acid

3.95 ± 1.06

4.27 ± 1.28

3.87 ± 1.14

1.51 ± 0.71

2.89 ± 1.24

Vanillic acid

2.39 ± 0.95

Methoxyhydroquinone

2.43 ± 0.54

Unknown compounda

Detected

  1. The starting substrate concentration was 5 mmol/L. Mean values and standard deviations were calculated from three biological replicates
  2. aUnknown compound with a retention time of 4.39