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Fig. 2 | Microbial Cell Factories

Fig. 2

From: Metabolic engineering of Escherichia coli for de novo production of 3-phenylpropanol via retrobiosynthesis approach

Fig. 2

Enumeration of 3-phenylpropanol biosynthetic pathways. All of the four pathways were extending from l-phenylalanine and phenylpyruvate in E. coli native l-phenylalanine metabolism and depicted by RetroPath 2.0 [33]. Pathway I and II was automatically generated by retrosynthesis workflow of RetroPath 2.0 based on reactions from databases. Pathway III and IV were functional pathways in previous reports [23,24,25]. The reactions in pathways were represented by EC numbers. The compound names are as follows: 3-phenylpropanol (A), 3-phenylpropyl aldehyde (B), cinnamyl alcohol (C), 3-phenylpropionic acid (D), cinnamaldehyde (E), cinnamic acid (F), l-phenylalanine (G), 3-phenyllactic acid (H), phenylpyruvate (I)

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Microbial Cell Factories

ISSN: 1475-2859

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