Table 4 Metabolic network characteristics of iJB1325 and eciJB1325

Number of nodes

1749

3551

1661

3504

Number of edges

20,090

38,258

11,621

24,750

Average number of neighbors

10.046

11.084

6.497

7.849

Network diameter

10

10

15

16

Network radius

5

5

8

8

Characteristic path length

3.27

3.384

4.693

5.115

Clustering coefficient

0.549

0.629

0.354

0.558

Network density

0.006

0.003

0.004

0.002

Network heterogeneity

2.404

2.477

1.753

1.524

Network centralization

0.329

0.259

0.116

0.082