Fig. 6

Effects of rhIL-2, rhIL-15, IL-15/SuIL-15Rα-dFc, and IL-15/SuIL-15Rα-mFc on NK and CD8⁺ T cell proliferation. Human PBMCs from healthy donors (n = 6) were cultured for 7 days in the absence or presence of 50 IU/mL rhIL-2, 10 ng/mL rhIL-15 or 35.7 ng/mL IL-15/SuIL-15Rα-IgG4 Fc complexes, and the proliferation of CFSE⁺ NK cells and CFSE⁺ CD8⁺ T cells was measured by flow cytometry. a Results from one representative healthy donor. b Statistics on the proliferation of NK cells or CD8⁺ T cells from all healthy donors. All data points are means ± standard deviation. *: p < 0.05; **: p < 0.01; ***: p < 0.001