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Fig. 4 | Microbial Cell Factories

Fig. 4

From: Development of IL-15/IL-15Rα sushi domain-IgG4 Fc complexes in Pichia pastoris with potent activities and prolonged half-lives

Fig. 4

Pharmacokinetics analysis of rhIL-15, IL-15/SuIL-15Rα-dFc and IL-15/SuIL-15Rα-mFc. C57BL/6 J mice (male, 6–8 weeks of age, n = 4–9 for each group) were intravenously administered 0.28 mg/kg rhIL-15 or 1 mg/kg IL-15/SuIL-15Rα-IgG4 Fc complexes, and blood samples were collected at the indicated time points after injection. The concentration of IL-15 in serum was measured by ELISA. All data points are the means ± standard deviation of the concentrations

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