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Fig. 9 | Microbial Cell Factories

Fig. 9

From: Oral probiotic activities and biosafety of Lactobacillus gasseri HHuMIN D

Fig. 9

Biosynthetic pathways of different biogenic amines by L. gasseri HHuMIN D. Solid arrows indicate that the biosynthesis pathways of biogenic amine is effective and dashed arrows indicate invalid: TYDC tyrosine decarboxylase, DDC/TDC L-tryptophan decarboxylase, ldcC/cadA lysine decarboxylase, hdc HDC, histidine decarboxylase, glsA/GLS glutaminase, CPS1 carbamoyl-phosphate synthase, OTC/argF/argI ornithine carbamoyl transferase, argG/ASS1 argininosuccinate synthase, argH/ASL argininosuccinate lyase, rocF/arg arginase, ODC1/speC/speF ornithine decarboxylase, PAO/FMS1 polyamine oxidase, SMS spermine synthase, speE/SRM/SPE3 spermidine synthase, and metK S-adenosylmethionine synthetase. Whole genome sequencing of L. gasseri HHuMIN D was performed by Chunlab, Inc. (Seoul, Korea), which used PacBio Sequel Systems (Pacific Biosciences, Menlo Park, CA, USA) and analyzed using CLgenomics™ and EZBioCloud Apps programs (Chunlab, Seoul, Korea). Biosynthetic pathways of different biogenic amines were analyzed by matching with the KEGG pathway using complete genome sequencing of L. gasseri HHuMIN D via CL Genomics™ (ChunLab, Seoul, South Korea, 2004). The activities of related genes and substances produced can be inferred through the biosynthetic pathways provided by KEGG

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