Fig. 1
From: Synthesis of cembratriene-ol and cembratriene-diol in yeast via the MVA pathway
A schematic diagram of CBT-ol/CBT-diol synthesis in tobacco. Tobacco GGPP could be formed via MEP or MVA pathway. The MEP pathway derived GGPP was shown to be the precursor of CBT-ol/CBT-diol, but it is unknown whether GGPP from the MVA pathway could act as their precursor. Formation of CBT-ol from GGPP is catalyzed by CBTS1, and further synthesis of CBT-diol is catalyzed by CYP450. Both CBT-ol and CBT-diol have two structural isomers