Fig. 1From: Amphotericin B biosynthesis in Streptomyces nodosus: quantitative analysis of metabolism via LC–MS/MS based metabolomics for rational designStructures and the antibiotic biosynthesis gene cluster of amphotericin. a Structures of amphotericin B and amphotericin A, which are different in the reduction of C28–C29 double bond. b The amphotericin biosynthesis gene cluster is organized with PKS genes, post-PKS modification genes, transporter and regulator genes and other ORF genes, which are described by white arrow, white arrow with line, grey arrow and black arrow, respectivelyBack to article page