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Table 2 Design space, factors and responses including standard deviations from full factorial study comprising 11 + 3 additional bioreactor cultivations

From: Optimal process design space to ensure maximum viability and productivity in Penicillium chrysogenum pellets during fed-batch cultivations through morphological and physiological control

NameP/V [W/m3]Qs [gs/gx/h]dO2 [%]Mean pellet size [µm]Mean C [−]Mean vl [µm]Mean qp [gP/gX/d]
LLL3700.0175.0150.7 ± 9.50.51 ± 0.0231.5 ± 5.10.18 ± 0.12
HLL20120.0185.0129.3 ± 4.50.88 ± 0.0338.6 ± 3.00.19 ± 0.09
LHL3700.0405.0183.1 ± 9.30.52 ± 0.0222.1 ± 9.80.02 ± 0.01
HHH119000.04240.0135.7 ± 9.00.61 ± 0.0333.6 ± 3.10.41 ± 0.24
LLH3700.01540.0161.7 ± 9.00.48 ± 0.0240.1 ± 4.20.29 ± 0.23
MMH15350.03840.0136.5 ± 5.80.48 ± 0.0133.1 ± 3.00.38 ± 0.17
LHH3700.04540.0142.3 ± 5.30.44 ± 0.0328.9 ± 2.90.29 ± 0.17
HHH227000.04940.0128.7 ± 5.10.85 ± 0.0231.7 ± 2.30.34 ± 0.21
CP115350.03422.5136.5 ± 8.00.49 ± 0.0536.4 ± 3.10.44 ± 0.19
CP215350.03322.5136.1 ± 5.80.48 ± 0.0233.3 ± 3.50.40 ± 0.16
CP315350.03522.5129.6 ± 4.50.49 ± 0.0338.1 ± 3.00.48 ± 0.21
MHH11130.05440.0128.0 ± 5.10.49 ± 0.0228.0 ± 3.10.13 ± 0.09
MMM15350.02622.5141.7 ± 6.90.50 ± 0.0340.1 ± 4.20.29 ± 0.13
HHH330000.05040.0120.8 ± 5.10.88 ± 0.0331.0 ± 3.20.30 ± 0.19