Skip to main content

Table 1 The IC50 value (μL/mL) by CFSs of LAB on Caco-2 and HT-29 cells

From: Metabolite secretions of Lactobacillus plantarum YYC-3 may inhibit colon cancer cell metastasis by suppressing the VEGF-MMP2/9 signaling pathway

Concentration (μL/mL)

Cell lines

Strains

80

100

200

300

400

500

600

700

IC50 value

Caco-2

GG

–

1.63 ± 0.03

22.83 ± 0.19

40.28 ± 0.13

53.76 ± 0.04

61.62 ± 0.08

84.53 ± 0.15

92.22 ± 0.06

344.81 ± 0.08

 

M3

–

7.28 ± 0.06

27.52 ± 0.13

51.16 ± 0.09

68.30 ± 0.12

72.83 ± 0.04

89.32 ± 0.11

96.48 ± 0.13

291.66 ± 0.13

 

YYC-3

–

5.27 ± 0.01

26.39 ± 0.06

48.23 ± 0.16

60.27 ± 0.08

69.44 ± 0.11

88.10 ± 0.13

94.72 ± 0.09

312.78 ± 0.06

 

MRS

–

–

–

–

–

–

–

0.02 ± 0.001

–

HT-29

GG

–

3.41 ± 0.03

12.75 ± 0.22

39.47 ± 0.12

50.11 ± 0.16

73.59 ± 0.13

82.93 ± 0.09

95.37 ± 0.12

358.21 ± 0.08

 

M3

–

3.16 ± 0.01

10.73 ± 0.08

43.21 ± 0.12

50.09 ± 0.11

75.28 ± 0.18

86.81 ± 0.11

92.42 ± 0.17

349.88 ± 0.21

 

YYC-3

–

9.77 ± 0.01

30.69 ± 0.10

63.73 ± 0.08

72.71 ± 0.13

80.10 ± 0.02

89.73 ± 0.07

93.58 ± 0.06

259.91 ± 0.10

 

MRS

–

–

–

–

–

–

–

–

–

  1. CCK8 was used to carried out and using Logit of probit regression in SPSS19.0