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Fig. 5 | Microbial Cell Factories

Fig. 5

From: Metabolite secretions of Lactobacillus plantarum YYC-3 may inhibit colon cancer cell metastasis by suppressing the VEGF-MMP2/9 signaling pathway

Fig. 5

Protein secretion of MMP2, MMP9, and VEGFA and activity of MMPs by colon cancer cells treated with Lactobacillus CFS. a Caco-2 protein secretion; b HT-29 protein secretion; c Caco-2 MMPs activity. d HT-29 MMPs activity. ELISA analysis was performed to determine changes in protein secretion of MMP2, MMP9, and VEGFA and gelatin zymography was used to test the activity of MMPs in colon cancer cells treated with Lactobacillus CFS (untreated group is the negative control and the 5-FU treatment group is the positive control; error bars represent mean of each group ± SD of three independent experiments; a–e, f–i, A–E, different letters in bars mean P < 0.05 (significant differences) by One-way ANOVA in the same group

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Microbial Cell Factories

ISSN: 1475-2859

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