Table 1 MIMOSA identified taxonomic contributors for differential abundance metabolites
From: Effect of diet and intestinal AhR expression on fecal microbiome and metabolomic profiles
| Comparison | Metabolite name | Species | Synthesis genes | Degradation genes |
|---|---|---|---|---|
| HFD AhRKO Week 8 vs. HFD WT Week 8 | Anthranilate |
OTU1000113 p__Firmicutes; c__Clostridia; o__Clostridiales |
K07130 Arylformamidase | |
| HFD AhRKO Week 8 vs. HFD WT Week 8 | Anthranilate |
OTU10485 p__Proteobacteria; c__Deltaproteobacteria; o__Desulfovibrionales; f__Desulfovibrionaceae |
K07130 Arylformamidase | |
| HFD AhRKO Week 8 vs. HFD WT Week 8 | Tryptamine |
OTU358757 p__Verrucomicrobia; c__Verrucomicrobiae; o__Verrucomicrobiales; f__Verrucomicrobiaceae; g__Akkermansia; s__muciniphila |
K00274 Monoamine oxidase | |
| HFD AhRKO Week 8 vs. LFD AhRKO Week 8 | 4,6-Dihydroxyquinoline |
OTU358757 p__Verrucomicrobia; c__Verrucomicrobiae; o__Verrucomicrobiales; f__Verrucomicrobiaceae; g__Akkermansia; s__muciniphila |
K00274 Monoamine oxidase | |
| HFD AhRKO Week 8 vs. LFD AhRKO Week 8 | Adenine |
OTU10485 p__Proteobacteria; c__Deltaproteobacteria; o__Desulfovibrionales; f__Desulfovibrionaceae |
K01486 Adenine deaminase | |
| HFD AhRKO Week 8 vs. LFD AhRKO Week 8 | Adenine |
OTU1107703 p__Firmicutes; c__Erysipelotrichi; o__Erysipelotrichales; f__Erysipelotrichaceae; g__Allobaculum |
K01486 adenine deaminase | |
| HFD AhRKO Week 26 vs. HFD WT Week 26 | Biotin |
OTU1067143 p__Bacteroidetes; c__Bacteroidia; o__Bacteroidales; f__Rikenellaceae |
K03524 Biotin—[acetyl-CoA-carboxylase] ligase | |
| HFD AhRKO Week 26 vs. HFD WT Week 26 | Biotin |
OTU100567 p__Firmicutes; c__Clostridia; o__Clostridiales; f__Ruminococcaceae; g__Ruminococcus |
K03524 Biotin—[acetyl-CoA-carboxylase] ligase | |
| HFD AhRKO Week 26 vs. LFD AhRKO Week 26 | Taurine |
OTU1000113 p__Firmicutes; c__Clostridia; o__Clostridiales |
K01442 Choloylglycine hydrolase | |
| HFD AhRKO Week 26 vs. LFD AhRKO Week 26 | Taurine |
OTU10485 p__Proteobacteria; c__Deltaproteobacteria; o__Desulfovibrionales; f__Desulfovibrionaceae |
K00681 Glutathione hydrolase | |
| HFD AhRKO Week 26 vs. LFD AhRKO Week 26 | 17alpha,21-Dihydroxypregnenolone |
OTU102407 p__Bacteroidetes; c__Bacteroidia; o__Bacteroidales; f__Bacteroidaceae; g__Bacteroides |
K01822 steroid Delta-isomerase |