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Fig. 2 | Microbial Cell Factories

Fig. 2

From: Whole-genome and enzymatic analyses of an androstenedione-producing Mycobacterium strain with residual phytosterol-degrading pathways

Fig. 2

Genomic analysis of Mycobacterium sp. HGMS2. a Distribution of annotated ncRNA genes, COG gene, GC content and GC skew of M. neoaurum HGMS2. From outside to inside, the first circle indicates the distribution of ncRNA in the positive strand, including tRNA, three types of rRNA and sRNA (refer to the color codes on the right side); the second circle represents the distribution of the positive-stranded COG annotation genes, distinguished by different colors; the third circle represents the negative strand, the distribution of the COG annotated genes; the fourth circle indicates the distribution of the negative-stranded ncRNA; the fifth circle (black) indicates the GC content, with the average GC as the baseline, where the outwardly protruding means higher than the average, the inwardly protruding means lower than the average; the sixth circle is the GC skew value, where purple means less than 0, green means more than 0. b Heatmap comparison of the special genes of HGMS2 with those from four other mycobacteria, i.e., Mycobacterium sp. H37Rv, Mycobacterium sp. NRRL B-3805 (as reference), Mycobacterium sp. MCS and Mycobacterium sp. KMS. c Phylogenetic tree comparing HGMS2 with the aforementioned four mycobacteria. d Distribution of functional genes in the HGMS2 genome predicted by KEGG. A detailed classification of genes is summarized in Additional file 1: Table S4

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