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Table 1 Proteins triggering membrane proliferation in prokaryotes

From: Inducible intracellular membranes: molecular aspects and emerging applications

Protein Type Origin Expressed Morphology Protein arrangement Lipid composition Refs.
Fumarate Reductase TM E. coli E. coli Tubules Helical (10 units per turn) CL enrichment (~ 15% mol) [96, 116]
Succinate Dehydrogenase TM E. coli E. coli Tubules and Vesicles [117]
Mannitol Permease TM E. coli E. coli Vesicles [190]
P6 (sp6.6 gene product) TM Phage PM2 E. coli Vesicles Unknown alone.
Cage-forming protein associated with P3
[108]
P9 and P12 TM Phage φ6 P. syringae
E. coli
Vesicles CL enrichment (~ 10% mol in P.pseudoalcaligenes infected by phage φ6) [3, 112,113,114]
AlkB (alkane oxidation system) TM P. oleovorans E. coli Vesicles CL enrichment (not quantified) [191]
Tsr chemotaxis receptor TM E. coli E. coli Inner membrane invaginations Crystalline pseudohexagonal (3 dimers of Tsr per repeating unit) [125, 128]
sn-glycerol-3-P acyltransferase TM E. coli E. coli Tubules Helical (6 dimers per turn) No changes.
Dependent on phage heat shock protein (PspA).
[120, 121, 192]
(b subunit of) F0F1 ATP synthase TM E. coli E. coli Tubules and vesicles Unknown. Dimer formation CL enrichment (~ 24% mol) [6, 122, 123, 149]
P3A M FMDV E. coli Onion-like vesicles Unknown. Possible oligomerization? [97]
Caveolin-1 M H. sapiens E. coli Vesicles Well-defined supramolecular cage (160 monomers per cage) PG and lysophospholipids enrichment (not quantified) [104, 105]
MurG M E. coli E. coli Vesicles CL enrichment (~ 22% mol) [137]
LpxB M E. coli and
H. influenzae
E. coli Tubules and vesicles PG and CL enrichment (not quantified) [138]
PmtA M A. tumefacensis A. tumefacensis Vesicles CL needed for membrane proliferation (not quantified) [139]
alMGS M A. laidlewii E. coli Vesicles PG and CL enrichment (not quantified) [140,141,142, 193]