Table 1 Proteins triggering membrane proliferation in prokaryotes

Fumarate Reductase

TM

E. coli

E. coli

Tubules

Helical (10 units per turn)

CL enrichment (~ 15% mol)

[96, 116]

Succinate Dehydrogenase

TM

E. coli

E. coli

Tubules and Vesicles

–

–

[117]

Mannitol Permease

TM

E. coli

E. coli

Vesicles

–

–

[190]

P6 (sp6.6 gene product)

TM

Phage PM2

E. coli

Vesicles

Unknown alone.

Cage-forming protein associated with P3

–

[108]

P9 and P12

TM

Phage φ6

P. syringae

E. coli

Vesicles

–

CL enrichment (~ 10% mol in P.pseudoalcaligenes infected by phage φ6)

[3, 112,113,114]

AlkB (alkane oxidation system)

TM

P. oleovorans

E. coli

Vesicles

–

CL enrichment (not quantified)

[191]

Tsr chemotaxis receptor

TM

E. coli

E. coli

Inner membrane invaginations

Crystalline pseudohexagonal (3 dimers of Tsr per repeating unit)

–

[125, 128]

sn-glycerol-3-P acyltransferase

TM

E. coli

E. coli

Tubules

Helical (6 dimers per turn)

No changes.

Dependent on phage heat shock protein (PspA).

[120, 121, 192]

(b subunit of) F₀F₁ ATP synthase

TM

E. coli

E. coli

Tubules and vesicles

Unknown. Dimer formation

CL enrichment (~ 24% mol)

[6, 122, 123, 149]

P3A

M

FMDV

E. coli

Onion-like vesicles

Unknown. Possible oligomerization?

–

[97]

Caveolin-1

M

H. sapiens

E. coli

Vesicles

Well-defined supramolecular cage (160 monomers per cage)

PG and lysophospholipids enrichment (not quantified)

[104, 105]

MurG

M

E. coli

E. coli

Vesicles

–

CL enrichment (~ 22% mol)

[137]

LpxB

M

E. coli and

H. influenzae

E. coli

Tubules and vesicles

–

PG and CL enrichment (not quantified)

[138]

PmtA

M

A. tumefacensis

A. tumefacensis

Vesicles

–

CL needed for membrane proliferation (not quantified)

[139]

alMGS

M

A. laidlewii

E. coli

Vesicles

–

PG and CL enrichment (not quantified)

[140,141,142, 193]