Skip to main content
Fig. 1 | Microbial Cell Factories

Fig. 1

From: TAK-242 ameliorates DSS-induced colitis by regulating the gut microbiota and the JAK2/STAT3 signaling pathway

Fig. 1

TAK-242 improved the performance of DSS-induced colitis. a Molecular structure of TAK 24. b, c Morphology and length of colon in each group. d Body weight change in each group. e DAI of each group. The data are expressed as the means ± SEM from ten mice per group and at least three independent experiments. Compared with the control group, DSS group exhibited significant weight loss, diarrhea, colitis manifestations with bloody stool, shortened colon and increased DAI (*p < 0.05, **p < 0.01, ***p < 0.001). Compared with the DSS group, the groups treated with different doses ofTAK-242 had significantly relieved signs and symptoms of DSS-induced colitis (#p < 0.05, ##p < 0.01, ###p < 0.001)

Back to article page

Microbial Cell Factories

ISSN: 1475-2859

Contact us