Fig. 4
From: Biosynthetic engineering of the antifungal, anti-MRSA auroramycin
Extender unit engineering of the auroramycin PKS. a Polyketide synthase assembly. b AT complementation schematic (left: native AT in modular PKS, right, complementation of inactivated AT by trans-acting AT). c LCMS spectra of the auroramycin-producing strain compared to AT6°, AT9° and AT10° strains complemented by dszsAT. KS ketosynthase, AT acyltransferase, KR ketoreductase, ACP acyl carrier protein, DH dehydratase, ER enoyl reductase, TE thioesterase, mAT malonyl CoA-specific acyltransferase