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Fig. 8 | Microbial Cell Factories

Fig. 8

From: ClC transporter activity modulates histidine catabolism in Lactobacillus reuteri by altering intracellular pH and membrane potential

Fig. 8

Proposed model of interactions among L. reuteri’s HDC proteins and ClC transporters. Phenotypic data suggest that EriC dominates over EriC2 in control of membrane potential, while EriC2 seems to play a greater role than its counterpart in controlling intracellular pH. EriC and EriC2 appear to use opposing transport mechanisms with EriC being a proton exporter/chloride importer while EriC2 exhibits the behavior of a proton importer/chloride exporter. Despite differing transport mechanisms, both play a role in maintaining electrochemical balance within the cell during histamine production and as controllers of intracellular pH in this system

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Microbial Cell Factories

ISSN: 1475-2859

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