Fig. 3From: Phosphate regulator PhoP directly and indirectly controls transcription of the erythromycin biosynthesis genes in Saccharopolyspora erythraeaThe regulatory effect of nitrogen on erythromycin production is mediated by PhoP. a GlnR–PhoP-ery cascaded regulation; b The ErA production of WT, ΔglnR, CglnR, OphoP, and ΔglnR:OphoP cultivated in TSB medium for 3 days. c The transcriptional profiles of ery cluster genes in WT and ΔglnR cultivated in TSB medium for 3 days. *P < 0.05, **P < 0.01Back to article page