Fig. 6
From: Synthetic control devices for gene regulation in Penicillium chrysogenum
Development of RFP/GFP fluorescence over time during growth of selected P. chrysogenum strains. a The strains contain control devices with different CPs. b The strains express RFP under a synthetic promoter containing 1 (open diamonds), 5 (closed symbols, in 5′→3′ direction; open with a plus in 3′→5′ direction), 11 (open symbols) or no (stars) QUAS elements upstream of the Pc_pcbC CP. c The strains express RFP under the full promoters of pcbC (red triangles down) or pcbAB (blue triangles down) or under a synthetic promoter containing 5xQUAS elements upstream of the Pc_pcbC (red circles) or Pc_pcbAB (blue diamonds) CPs. Sold lines indicate mean values for at least 3 independent cultures, the dashed lines show the standard error. The difference in expression of RFP of all strains expressing functional control devices, was significant (p < 0.0001) compared to the base strain (strain no. 2, 40s_5Q_pcbC)