Enhanced production of styrene by engineered Escherichia coli and in situ product recovery (ISPR) with an organic solvent

Table 1 Overview on de novo production of styrene in bacterial hosts

Strain	Culture mode	Solvent for extraction	Max. titers (mg/L)	Productivity (mg/L/hr)	Refs.
E. coli YHP05	Flask	n-Dodecane	1700	35.4	This work
E. coli YHP05	Fed-batch fermentation	n-Dodecane	5300	88.3	This work
E. coli NST74	Flask	–	260	9.0	[6]
E. coli NST74	Flask	bis(2-Ethylhexyl)phthalate	836	17.4	[8]
E. coli BL21(DE3)	Flask	Isopropyl myristate	350	7.3	[9]
S. cerevisiae	Flask	–	29	0.6	[7]

ISSN: 1475-2859