Equilibrium of the intracellular redox state for improving cell growth and l-lysine yield of Corynebacterium glutamicum by optimal cofactor swapping

Table 2 The DCW (24 h or 48 h), l-lysine production (24 h or 48 h), maximal specific growth rate (μ_max.), maximal specific production rate of l-lysine (q_{Lys, max.}), maximal specific substrate uptake rate of glucose (q_{s, max.}) and glucose conversion efficiency (α) of C. glutamicum strains

C. glutamicum strains	DCW (g L⁻¹)		l-Lys yield (g L⁻¹)		μ_max ^a (h⁻¹)	q_{Lys, max.} ^b (g g⁻¹ h⁻¹)	q_{s, max.} ^c (g g⁻¹ h⁻¹)	α^d (%)
C. glutamicum strains	24 h	48 h	24 h	48 h	μ_max ^a (h⁻¹)	q_{Lys, max.} ^b (g g⁻¹ h⁻¹)	q_{s, max.} ^c (g g⁻¹ h⁻¹)	α^d (%)
JL-6	54.3 ± 6.5	47.1 ± 3.8	21.4 ± 4.1	85.6 ± 3.7	0.23	0.26 ± 0.05	0.80 ± 0.15	32.9
RG	26.3 ± 3.6	35.2 ± 4.5	27.2 ± 6.3	92.5 ± 2.6	0.14	0.42 ± 0.08	0.65 ± 0.32	43.6
RGI	60.3 ± 5.8	52.5 ± 2.8	53.1 ± 7.9	121.4 ± 4.8	0.31	0.53 ± 0.06	0.93 ± 0.24	50.0

All data are meaning values of three determinations of three independent experiments with ± SD
^aThe maximal specific growth rate of cell in the whole fermentation cycle
^bThe maximal specific production rate of l-lysine in the whole fermentation cycle
^cThe maximal specific substrate uptake rate of glucose in the whole fermentation cycle
^dThe conversion rate of glucose into l-lysine after cultivating 48 h

ISSN: 1475-2859