Skip to main content
Fig. 1 | Microbial Cell Factories

Fig. 1

From: Disruption of poly (3-hydroxyalkanoate) depolymerase gene and overexpression of three poly (3-hydroxybutyrate) biosynthetic genes improve poly (3-hydroxybutyrate) production from nitrogen rich medium by Rhodobacter sphaeroides

Fig. 1

PHB biosynthetic pathway. First, ACAT transfers an acetyl group from one molecule of acetyl-CoA to the acetyl group of a second acetyl-CoA and produces acetoacetyl-CoA and CoASH. Second, AACR reduces the acetoacetyl group of acetoacetyl-CoA and produces (R)-3-hydroxybutanoyl-CoA. Finally, PHAP polymerizes several (R)-3-hydroxybutanoyl groups from (R)-3-hydroxybutanoyl-CoA molecules and produces PHB and CoASH. Synthesized PHB is degraded by PHADP to form (R)-3-((R)-3-hydroxybutanoyloxy) butanoate

Back to article page