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Table 2 Solutions given by Box–Behnken Design for medium composition

From: Large-scale production of tauroursodeoxycholic acid products through fermentation optimization of engineered Escherichia coli cell factory

Solution no. Suggested concentration (g/L) Expected Desirability
Glucose Glycerol Tryptone Yeast extract OD600 Conversion efficiency
1 0.00 28.43 0.00 20.00 7.45 22.7% 0.23
2 0.01 27.87 0.00 20.00 7.44 22.7% 0.23
3 0.00 26.99 0.00 20.0 7.41 22.65 0.23
4 0.00 30.00 0.00 19.37 7.55 22.45 0.22
5 0.00 24.17 0.00 19.98 7.36 22.44 0.22
6 0.17 29.84 0.01 20.0 7.57 22.30 0.22
7 0.20 30.00 0.00 20.0 7.58 22.23 0.22
8 0.00 30.00 0.00 18.70 7.60 22.13 0.22
9 0.00 21.04 0.04 19.97 7.34 22.09 0.22
10 0.00 30.00 2.40 20.00 7.42 22.00 0.22
  1. The top 10 of 55 solutions were listed and the selected one was highlighted in italics