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Fig. 4 | Microbial Cell Factories

Fig. 4

From: Comparative proteome analysis in an Escherichia coli CyDisCo strain identifies stress responses related to protein production, oxidative stress and accumulation of misfolded protein

Fig. 4

Analysis of E. coli CyDisCo proteome changes in the strains expressing scFv and misfolded scFv vs. an empty plasmid control. Venn diagram showing the number of unique and shared proteins identified in E. coli CyDisCo strains (a). Proteome changes are shown as the change in protein abundance (Δlog2 ratio) of strains expressing: TorA-scFv vs. control (b) and TorA-mf_scFv vs. control (c). Changes in protein abundance were color coded: orange indicates increase in the scFv and scFv (misfolded) proteome, gray indicates unidentified, and blue indicates decrease in the scFv and scFv (misfolded) proteome. Additionally, proteins which were identified in scFv expressing strains but not in the control strain were colored red (ON proteins) and proteins identified only in control strain but not in scFv expressing strains were colored navy blue (OFF proteins). The treemap legend shows the classification of the E. coli proteome according to TIGRfam annotations with manual adjustments (d)

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Microbial Cell Factories

ISSN: 1475-2859

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