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Fig. 2 | Microbial Cell Factories

Fig. 2

From: Rational construction of genome-reduced and high-efficient industrial Streptomyces chassis based on multiple comparative genomic approaches

Fig. 2

Multiple genome alignments by Mauve 2.3.1. Comparative analysis of three taxonomically distinct Streptomyces genomes, S. avermitilis MA-4680, S. coelicolor A3(2), and S. chattanoogensis L10, revealed a conserved core region of ∼ 6.0 Mb in which the majority of the genes are highly conserved with a high degree of synteny and two dispensable (accessory) genome regions located at sub-telomeric regions of the chromosomal ends. The oriC and dnaA box-like sequences are located at 5,293,751–5,294,960 bp which has about a deviation of 770 Kb to the center of chromosome, so the genome structure shows asymmetry

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