Skip to main content

Table 2 Final process-response measurements at every experimentally designed condition

From: Saccharomyces cerevisiae morphological changes and cytokinesis arrest elicited by hypoxia during scale-up for production of therapeutic recombinant proteins

EOR

measurements

10,000 L

(n = 6)

10 L

(n = 6)

DO 25%

DO 12.5%

DO 8.5%

DO 5.0%

DCW (g/kg)

140.6

137.3

140.5

145.5

WCW (g/kg)

719.1

567.4

618.4

671.4

WCW/DCW ratio

(± SEM)

5.12

(± 0.06)

4.13

(± 0.10)

4.40

(± 0.10)

4.62

(± 0.18)

Viability (%)

(± SEM)

93.2

(± 1.1)

86.9

(± 2.0)

89.8

(± 1.0)

91.4

(± 0.5)

  1. EOR stands for end of run, 82 h EFT. SEM means Standard Error of the Mean, DCW and WCW values are averages based on two determinations per time point (EFT) from three experiments
Back to article page

Microbial Cell Factories

ISSN: 1475-2859

Contact us