Enhancing the production of cephalosporin C through modulating the autophagic process of Acremonium chrysogenum

Table 1 Effects of supplemented carbon/nitrogen sources on conidiation of A. chrysogenum

Conidia formation in WT, ∆Acatg8 and Acatg8C grown on the LPE medium supplemented with different carbon/nitrogen sources. Glucose, sucrose, inositol or mannitol was supplemented at the final concentration of 1%. Ammonium chloride (NH₄Cl), niter nitrate (NaNO₃), ammonium nitrate (NH₄NO₂), methionine (Met) or proline (Pro) was added in the LPE medium at the final concentration of 1%. Numbers of conidia were counted after 7 days incubation. CK, the medium without supplementation of carbon/nitrogen sources. The data are derived from the average of three independent experiments. The asterix indicates that the differences between strains are significant. p < 0.001 ***; p < 0.01 **; p < 0.05 *

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