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Fig. 1 | Microbial Cell Factories

Fig. 1

From: In silico model-guided identification of transcriptional regulator targets for efficient strain design

Fig. 1

Schematic workflow of h-BeReTa. a Acquisition of gene-expression data for producer and non-producer, processing TRN information, determination of nRS values. b Constraint-based flux analysis mediated determination of nGAPs for a desired product using GEM with necessary GPRs. c Calculation of the effect of TRs on product flux (TREs), and therefore global TREs using nRS, nGAP values in combination with TR-hierarchy information

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Microbial Cell Factories

ISSN: 1475-2859

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