Elucidating redox balance shift in Scheffersomyces stipitis’ fermentative metabolism using a modified genome-scale metabolic model

Table 3 Comparison of iDH814 xylitol results to experimental data

Case	Y_E/S experiment	Xylitol experimental (mmol/gCDW/h)	Xylitol prediction (mmol/gCDW/h)	Ratio of XR NADPH/NADH	OUR
1	0.328	0.1408	0.1408	0.94	2.33
2	0.358	0.0934	0.0935	0.207	1.64
3	0.376	0.0115	0.0116	0.11	1.42
4	0.437	0.0172	0.0173	0.11	0.50

Y_E/S is the ethanol yield, where xylose is the substrate (S). Xylose reductase (XR) redox ratio and oxygen uptake rate (OUR) were varied. Minimized the error between ethanol yield of experiment and prediction from iDH814, then examined the xylitol productions from experiments and those predicted by iDH814

ISSN: 1475-2859