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Table 1 Product formation of naringenin and downstream metabolites in S. cerevisiae strains.

From: Engineering de novo anthocyanin production in Saccharomyces cerevisiae

µM

IMX106

IMX106-F

IMX106-FD

IMX106-FDA

IMX106-FDA3

Naringenin

23.4 ± 1.4

7.8 ± 0.1

7.7 ± 0.6

6.5 ± 0.3

3.1 ± 1.0

DHK

–

18.5 ± 0.1

17.5 ± 0.9

8.5 ± 0.00

9.8 ± 0.8

Kaempferol

–

–

–

11.7 ± 0.5

4.4 ± 1.0

K3G

–

–

–

–

2.3 ± 0.2

Pelargonidin

–

–

–

0.07 ± 0.00

0.85 ± 0.03

P3G

–

–

–

–

0.05 ± 0.00

  1. Strains IMX106, IMX106-F, IMX106-FD, IMX106-FDA and IMX106-FDA3 were grown in 10 mL shake-flask cultures. The whole culture was extracted after 65 h of culturing at 30 °C. Metabolite concentrations of naringenin, dihydrokaempferol (DHK), kaempferol, kaempferol 3-O-glucoside (K3G), pelargonidin and pelargonidin 3-O-glucoside (P3G) expressed in µM were measured by HPLC. Data represents the average ± mean deviation of independent biological triplicates
  2. – not detected