Fig. 6

In vivo function of the regulatory genes rdmACDEF. a HPLC analysis of the fermentation products from (i) the standard of RDM A; (ii) WT; (iii) ΔrdmA; (iv) ΔrdmA complemented (ΔrdmA + rdmA); and (v) rdmA overexpression (WT + rdmA) strains. b HPLC analysis of the fermentation products from (i) the standard of RDM A; (ii) WT; (iii) ΔrdmF; (iv) ΔrdmF + rdmF; and (v) WT + rdmF. c HPLC analysis of the fermentation products from gene inactivation mutant strains of rdmCDE. (i) the standard of RDM A; (ii) WT; (iii) ΔrdmC; (iv) ΔrdmD; (v) ΔrdmE. d Production of RDM A (1) in the rdmAEF-engineered strains