Fig. 1

The biosynthetic pathways of l-isoleucine and metabolism of propionyl-CoA in C. glutamicum. The genes that were significantly regulated in C. glutamicum WM001 are shown together with their log₂R values, using C. glutamicum ATCC13869 as a control. The up-regulated genes are shown in red, while the down-regulated genes are shown in black. The reactions shown in blue exist in WM001/pDXW-8-phaCAB but not in C. glutamicum WM001