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Fig. 3 | Microbial Cell Factories

Fig. 3

From: Metabolome analysis-based design and engineering of a metabolic pathway in Corynebacterium glutamicum to match rates of simultaneous utilization of d-glucose and l-arabinose

Fig. 3

Metabolic profile of aerobically growing wild-type strain C. glutamicum ATCC 31831. Relative abundance of metabolic intermediates in C. glutamicum cells during aerobic growth in BT medium containing either d-glucose (open columns) or l-arabinose (gray columns) as the sole carbon source are shown. For the profiling experiment, the wild-type strain was grown aerobically to late log phase in A medium containing d-glucose (20 g/L) and l-arabinose (20 g/L), and the culture was then inoculated to an initial OD600 of 0.2 into BT medium containing either d-glucose (20 g/L) or l-arabinose (20 g/L) as the sole carbon source. The cells were harvested at mid log phase (OD600 = 1.5) and subjected to metabolic profiling. Data are presented as average ± standard deviation calculated from the results of triplicate individual experiments. Single and double asterisks indicate p values of < 0.05 and < 0.01, respectively

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