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Fig. 1 | Microbial Cell Factories

Fig. 1

From: Engineering CRISPR interference system in Klebsiella pneumoniae for attenuating lactic acid synthesis

Fig. 1

Glycerol and lactic acid pathways in Klebsiella pneumoniae. 3-HPA, 3-hydroxypropionaldehyde; 3-HP, 3-hydroxypropionic acid; 1,3-PDO, 1,3-propanediol; G-3-P, sn-glycerol 3-phosphate; DHA, dihydroxyacetone; DHAP, dihydroxyacetone phosphate; PEP, phosphoenolpyruvate; Pyr, pyruvate; 2,3-BDO, 2,3-butanediol; ldhA, d-lactate dehydrogenase gene; pmd, l-lactate dehydrogenase gene; mgsA, methylglyoxal synthase gene; aldA, lactaldehyde dehydrogenase gene. Red cross indicates enzyme genes to be repressed by CRISPRi system

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